Gene/Proteome Database (LMPD)

LMPD ID
LMP010652
Gene ID
828213
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
GLNB1-like protein
Gene Symbol
GLB1
Synonyms
GLNB1 homolog; PII; PII PROTEIN; T7B11.16; T7B11_16
Alternate Names
GLNB1-like protein
Chromosome
4
Summary
encodes a PII protein that may function as part of a signal transduction network involved in perceiving the status of carbon and organic nitrogen. Forms a protein complex with N-acetylglutamate kinase and regulates the kinase activity by relieving the feedback inhibition of the kinase by arginine. Regulates acetyl-CoA carboxylase activity.
Orthologs
View orthologs and multiple alignments for GLB1

Proteins

GLNB1-like protein
Refseq ID NP_192099
Protein GI 15234360
UniProt ID Q9ZST4
mRNA ID NM_116421
Length 196
RefSeq Status REVIEWED
MAASMTKPISITSLGFYSDRKNIAFSDCISICSGFRHSRPSCLDLVTKSPSNNSRVLPVVSAQISSDYIPDSKFYKVEAIVRPWRIQQVSSALLKIGIRGVTVSDVRGFGAQGGSTERHGGSEFSEDKFVAKVKMEIVVKKDQVESVINTIIEGARTGEIGDGKIFVLPVSDVIRVRTGERGEKAEKMTGDMLSPS

Gene Information

Entrez Gene ID
828213
Gene Name
GLNB1-like protein
Gene Symbol
GLB1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009507 IDA:TAIR C chloroplast
GO:0009534 IDA:TAIR C chloroplast thylakoid
GO:0005829 IDA:TAIR C cytosol
GO:0009536 IDA:TAIR C plastid
GO:0005524 IDA:UniProtKB F ATP binding
GO:0010307 IDA:TAIR F acetylglutamate kinase regulator activity
GO:0000287 IDA:UniProtKB F magnesium ion binding
GO:0009718 IMP:TAIR P anthocyanin-containing compound biosynthetic process
GO:0006807 ISS:TAIR P nitrogen compound metabolic process
GO:2000013 TAS:TAIR P regulation of arginine biosynthetic process via ornithine
GO:0042304 IMP:TAIR P regulation of fatty acid biosynthetic process
GO:0006808 IEA:InterPro P regulation of nitrogen utilization
GO:0042325 IDA:GOC P regulation of phosphorylation
GO:0006355 IEA:UniProtKB-KW P regulation of transcription, DNA-templated
GO:0009416 IEP:TAIR P response to light stimulus
GO:0009744 IEP:TAIR P response to sucrose
GO:0006351 IEA:UniProtKB-KW P transcription, DNA-templated

Domain Information

InterPro Annotations

Accession Description
IPR011322 Nitrogen regulatory PII-like, alpha/beta
IPR002187 Nitrogen regulatory protein PII
IPR017918 Nitrogen regulatory protein PII, conserved site
IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal

UniProt Annotations

Entry Information

Gene Name
GLNB1-like protein
Protein Entry
GLNB_ARATH
UniProt ID
Q9ZST4
Species
Arabidopsis

Comments

Comment Type Description
Disruption Phenotype No visible phenotype under normal growth condition, but increased sensitivity to elevated levels of nitrite. {ECO:0000269|PubMed:16133214}.
Function Participates in sensing carbon and organic nitrogen status and regulates some steps of primary carbon and nitrogen metabolism. Required for nitrite uptake in chloroplasts and regulates arginine biosynthesis through interaction with acetylglutamate kinase (NAGK) in chloroplasts. Regulates fatty acids synthesis in chloroplasts by interacting with the acetyl-CoA carboxylase complex and inhibiting acetyl-CoA carboxylase (ACCase) activity. {ECO:0000269|PubMed:16133214, ECO:0000269|PubMed:18325336, ECO:0000269|PubMed:9811909}.
Induction By light and sucrose. Down-regulated by treatment with amino acids. {ECO:0000269|PubMed:9811909}.
Interaction Q9SCL7:NAGK; NbExp=4; IntAct=EBI-701245, EBI-701276;
Similarity Belongs to the P(II) protein family. {ECO:0000255|PROSITE-ProRule:PRU00675}.
Subcellular Location Plastid, chloroplast {ECO:0000255|PROSITE- ProRule:PRU00675, ECO:0000269|PubMed:16377628, ECO:0000269|PubMed:9811909}.
Subunit Homodimer. Interacts with NAGK. Interaction with NAGK is dependent of MgATP and inhibited by 2-oxoglutarate, arginine, glutamate, citrate, and oxaloacetate. {ECO:0000269|PubMed:16377628, ECO:0000269|PubMed:17913711}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010652 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15234360 RefSeq NP_192099 196 GLNB1-like protein

Identical Sequences to LMP010652 proteins

Reference Database Accession Length Protein Name
GI:15234360 EMBL CBG07926.1 196 unnamed protein product [Arabidopsis thaliana]
GI:15234360 EMBL CBV13234.1 196 unnamed protein product [Arabidopsis thaliana]
GI:15234360 EMBL CBV21448.1 196 unnamed protein product [Arabidopsis thaliana]
GI:15234360 GenBank AEE82094.1 196 GLNB1-like protein [Arabidopsis thaliana]
GI:15234360 GenBank AGX81269.1 196 Sequence 62288 from patent US 8541208
GI:15234360 GenBank AGX99422.1 196 Sequence 79072 from patent US 8541208

Related Sequences to LMP010652 proteins

Reference Database Accession Length Protein Name
GI:15234360 GenBank EFH51210.1 196 hypothetical protein ARALYDRAFT_490384 [Arabidopsis lyrata subsp. lyrata]
GI:15234360 GenBank EOA19468.1 195 hypothetical protein CARUB_v10002012mg [Capsella rubella]
GI:15234360 RefSeq XP_002874951.1 196 hypothetical protein ARALYDRAFT_490384 [Arabidopsis lyrata subsp. lyrata]
GI:15234360 RefSeq XP_006286570.1 195 hypothetical protein CARUB_v10002012mg [Capsella rubella]
GI:15234360 RefSeq XP_010428940.1 193 PREDICTED: nitrogen regulatory protein P-II homolog [Camelina sativa]
GI:15234360 RefSeq XP_010456109.1 192 PREDICTED: nitrogen regulatory protein P-II homolog isoform X1 [Camelina sativa]