Gene/Proteome Database (LMPD)
LMPD ID
LMP010974
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Gene Symbol
Synonyms
F16B22.15
Alternate Names
probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Chromosome
2
EC Number
2.4.1.265
Proteins
| probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase | |
|---|---|
| Refseq ID | NP_181994 |
| Protein GI | 240254647 |
| UniProt ID | O80505 |
| mRNA ID | NM_130030 |
| Length | 506 |
| RefSeq Status | REVIEWED |
| MDHREKSDRRLLLWFFAVATAVKLLLIPSSRSTDFEVHRNWLAITNSLPLTKWYFDETSQWTLDYPPFFAYFERFLSIFARLVDPRIVDLQSGLDYNAESVIYFQRISVIVSDLCLLYGVYRLTRKLEPLKRNLICALVIWSPGLLIVDHIHFQYNGFLLGWLLLSISFLQEGRDLLGGFLFAVLLCFKHLFAVTAPVYFVYLLRHYCWSGLVTGFRRLVTIGAVVVAVFAAAYGPFIYHGQIQQVISRMFPFGRGLCHAYWAPNFWVFYIILDKGLAVLLRKLGYEIQIPSASFTGGLVGDSSPFAVLPQITPLTTFAMVLLAISPCLIKAWKKPHSGLVARWVAYAYTCGFLFGWHVHEKASLHFTIPLAIVAVQSLEDAKHYFLVSIVSCYSLYPLLYEPQEYPIKVLLLLLHSVVMWLGFAAQYTDYKAQKKETSEIKSKFRIGCFEKSYLMGLIIVEIVSQFLHPYFLGDKLPFLPLMLISTYCTVGIMYSWIWQLRKILT | |
Gene Information
Entrez Gene ID
Gene Name
probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005789 | IEA:InterPro | C | endoplasmic reticulum membrane |
| GO:0016021 | IEA:UniProtKB-KW | C | integral component of membrane |
| GO:0016758 | IEA:InterPro | F | transferase activity, transferring hexosyl groups |
| GO:0006486 | IEA:UniProtKB-UniPathway | P | protein glycosylation |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ath01100 | Metabolic pathways |
| ath00510 | N-Glycan biosynthesis |
| ko00510 | N-Glycan biosynthesis |
| ath_M00055 | N-glycan precursor biosynthesis |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR004856 | Glycosyl transferase, ALG6/ALG8 |
UniProt Annotations
Entry Information
Gene Name
probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Protein Entry
ALG8_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Catalytic Activity | Dolichyl beta-D-glucosyl phosphate + D-Glc- alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha- (1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)- D-Man-alpha-(1->6))-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D- GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = D-Glc-alpha- (1->3)-D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D- Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man- alpha-(1->2)-D-Man-alpha-(1->6))-D-Man-alpha-(1->6)]-D-Man-beta- (1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate. |
| Function | Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity). {ECO:0000250}. |
| Pathway | Protein modification; protein glycosylation. |
| Sequence Caution | Sequence=AAC27468.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
| Similarity | Belongs to the ALG6/ALG8 glucosyltransferase family. {ECO:0000305}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP010974 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 240254647 | RefSeq | NP_181994 | 506 | probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase |
Identical Sequences to LMP010974 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:240254647 | GenBank | AEC10452.1 | 506 | probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase [Arabidopsis thaliana] |
| GI:240254647 | SwissProt | O80505.3 | 506 | RecName: Full=Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; AltName: Full=Asparagine-linked glycosylation protein 8 homolog; AltName: Full=Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase; AltName: Full=Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase [Arabidopsis thaliana] |
Related Sequences to LMP010974 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:240254647 | GenBank | EFH58232.1 | 506 | hypothetical protein ARALYDRAFT_903892 [Arabidopsis lyrata subsp. lyrata] |
| GI:240254647 | GenBank | EOA26952.1 | 505 | hypothetical protein CARUB_v10023047mg [Capsella rubella] |
| GI:240254647 | RefSeq | XP_002881973.1 | 506 | hypothetical protein ARALYDRAFT_903892 [Arabidopsis lyrata subsp. lyrata] |
| GI:240254647 | RefSeq | XP_010506395.1 | 525 | PREDICTED: probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase [Camelina sativa] |
| GI:240254647 | RefSeq | XP_010508269.1 | 506 | PREDICTED: probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase [Camelina sativa] |
| GI:240254647 | RefSeq | XP_010518070.1 | 508 | PREDICTED: probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase [Camelina sativa] |