Gene/Proteome Database (LMPD)
Proteins
| UDP-3-O-acyl N-acetylglycosamine deacetylase family protein | |
|---|---|
| Refseq ID | NP_001185090 |
| Protein GI | 334182845 |
| UniProt ID | P0DKB9 |
| mRNA ID | NM_001198161 |
| Length | 326 |
| RefSeq Status | REVIEWED |
| MRLPVTVKATKPSFLVIWIRYSSAASSPTVSLNPSGRLQQTLAGSVEVKGKSLHSGKFSTVKLNPEIAGAGRFFEFRSRFIPASIEFAQESPLCTTLLKDELKIRTVEHLLSALEAKGVDNCRIQIESESSDDREVEVPIFDGSAKEWVDAIQGVGINAAQNHDGESVEKMVAHVNKPVYVCKNDTFVAAFPALETRITCGIDFPQVPAIGCQWFSWRPIHESSFAKDIASSRTFCVYEEVERMREAGLIKGGSLDNAIVCSAEHGWMNPPLRFDDEACRHKILDLIGDLSLVSRGGNGGLPVAHIVAYKAGHALHTDLARHLTMD | |
Gene Information
Entrez Gene ID
Gene Name
UDP-3-O-acyl N-acetylglycosamine deacetylase family protein
Gene Symbol
Species
Arabidopsis thaliana
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0005739 | IDA:UniProtKB | C | mitochondrion |
| GO:0008759 | IMP:UniProtKB | F | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity |
| GO:0009245 | IEA:UniProtKB-KW | P | lipid A biosynthetic process |
| GO:2001289 | IMP:UniProtKB | P | lipid X metabolic process |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ath01100 | Metabolic pathways |
Domain Information
UniProt Annotations
Entry Information
Gene Name
UDP-3-O-acyl N-acetylglycosamine deacetylase family protein
Protein Entry
LPXC1_ARATH
UniProt ID
Species
Arabidopsis
Comments
| Comment Type | Description |
|---|---|
| Alternative Products | Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=F4IAT8-1; Sequence=Displayed; Name=2; IsoId=F4IAT8-2; Sequence=VSP_022944, VSP_022945; Note=May be due to a competing donor splice site. No experimental confirmation available.; Name=3; IsoId=F4IAT8-3; Sequence=VSP_034100; Note=May be due to intron retention. No experimental confirmation available.; |
| Catalytic Activity | UDP-3-O-(3-hydroxytetradecanoyl)-N- acetylglucosamine + H(2)O = UDP-3-O-(3-hydroxytetradecanoyl)- glucosamine + acetate. |
| Function | Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential). {ECO:0000305}. |
| Miscellaneous | Plants silencing LPXC do not have altered morphology compared to wild-type plants when grown under normal growth conditions, but they do not accumulate 2,3- diacylglucosamine-1-phosphate. {ECO:0000305|PubMed:21709257}. |
| Pathway | Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. {ECO:0000269|PubMed:21709257}. |
| Sequence Caution | Sequence=AAG03124.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g24793 and At1g24800.; Evidence={ECO:0000305}; |
| Similarity | Belongs to the LpxC family. {ECO:0000305}. |
| Subcellular Location | Mitochondrion {ECO:0000269|PubMed:21709257}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP011061 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 334182845 | RefSeq | NP_001185090 | 326 | UDP-3-O-acyl N-acetylglycosamine deacetylase family protein |
Identical Sequences to LMP011061 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:334182845 | GenBank | AEE30582.1 | 326 | UDP-3-O-acyl N-acetylglycosamine deacetylase family protein [Arabidopsis thaliana] |
| GI:334182845 | SwissProt | P0DKB7.1 | 326 | RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2; AltName: Full=Protein LIPID X C2; Short=AtLpxC2; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 2; Flags: Precursor [Arabidopsis thaliana] |
| GI:334182845 | SwissProt | P0DKB8.1 | 326 | RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3; AltName: Full=Protein LIPID X C3; Short=AtLpxC3; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 3; Flags: Precursor [Arabidopsis thaliana] |
| GI:334182845 | SwissProt | P0DKB9.1 | 326 | RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 4; AltName: Full=Protein LIPID X C4; Short=AtLpxC4; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 4; Flags: Precursor [Arabidopsis thaliana] |
| GI:334182845 | SwissProt | F4IAT8.2 | 326 | RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1; AltName: Full=Protein LIPID X C1; Short=AtLpxC1; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 1; Flags: Precursor [Arabidopsis thaliana] |
| GI:334182845 | SwissProt | F4IAW1.2 | 326 | RecName: Full=Probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5; AltName: Full=Protein LIPID X C5; Short=AtLpxC5; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase 5; Flags: Precursor [Arabidopsis thaliana] |
Related Sequences to LMP011061 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:334182845 | GenBank | AEE30567.1 | 369 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana] |
| GI:334182845 | GenBank | AEE30573.1 | 369 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana] |
| GI:334182845 | GenBank | AEE30586.1 | 371 | probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5 [Arabidopsis thaliana] |
| GI:334182845 | RefSeq | NP_173884.5 | 369 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana] |
| GI:334182845 | RefSeq | NP_173878.6 | 369 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana] |
| GI:334182845 | RefSeq | NP_849706.3 | 371 | probable UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 5 [Arabidopsis thaliana] |