Gene/Proteome Database (LMPD)

LMPD ID
LMP011858
Gene ID
447807
Species
Danio rerio (Zebrafish)
Gene Name
solute carrier family 51, alpha subunit
Gene Symbol
slc51a
Synonyms
osta; fb57f06; zgc:92111; wu:fb57f06
Alternate Names
organic solute transporter subunit alpha; OST-alpha; solute carrier family 51 subunit alpha
Chromosome
24

Proteins

organic solute transporter subunit alpha
Refseq ID NP_001004546
Protein GI 52218944
UniProt ID Q66I08
mRNA ID NM_001004546
Length 326
RefSeq Status PROVISIONAL
METSNFTLFDPRCRAEAPFAIDAIKQLDIFGKVLYTVLTLMATASMLVFIEECIYIYKKVPAHKKSTIIWVTGVAPVMAIMSCLGMWVPRATMFTDMTSATYFAIVVFKFLILMIEEVGGDNAFLRRCEKQTFKISTGPCCCCCPCLPNVPITRRSLFILKLGSYQFALMKLVLTIFSIVLWTNGSFSLTNVSASGAAIWINSFIGVLTIIALWPVAIMFMHVREALRTLKIVPKYAMYQLVLILSQLQTAIINILALNGTIACSPPYSSQARGYMMSQQLLIVEMFIITLVTRVLYRRQYEPIPEPDDVEEKKTVLSSKKAIDVA

Gene Information

Entrez Gene ID
447807
Gene Name
solute carrier family 51, alpha subunit
Gene Symbol
slc51a
Species
Danio rerio

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 ISS:UniProtKB C endoplasmic reticulum membrane
GO:0016021 ISS:UniProtKB C integral component of membrane
GO:0005886 ISS:UniProtKB C plasma membrane
GO:0043234 ISS:UniProtKB C protein complex
GO:0046982 ISS:UniProtKB F protein heterodimerization activity
GO:0042803 ISS:UniProtKB F protein homodimerization activity
GO:0005215 ISS:UniProtKB F transporter activity
GO:0015721 ISS:UniProtKB P bile acid and bile salt transport
GO:0006810 ISS:UniProtKB P transport

Domain Information

InterPro Annotations

Accession Description
IPR005178 Organic solute transporter subunit alpha/Transmembrane protein 184

UniProt Annotations

Entry Information

Gene Name
solute carrier family 51, alpha subunit
Protein Entry
OSTA_DANRE
UniProt ID
Q66I08
Species
Zebrafish

Comments

Comment Type Description
Function Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. {ECO:0000250}.
Similarity Belongs to the OST-alpha family. {ECO:0000305}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Subunit Interacts with slc51b. The Ost-alpha/Ost-beta complex is a heterodimer composed of alpha (slc51a) and beta (slc51b) subunit (By similarity). {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP011858 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
52218944 RefSeq NP_001004546 326 organic solute transporter subunit alpha

Identical Sequences to LMP011858 proteins

Reference Database Accession Length Protein Name
GI:52218944 GenBank AAH81597.1 326 Zgc:92111 [Danio rerio]
GI:52218944 SwissProt Q66I08.1 326 RecName: Full=Organic solute transporter subunit alpha; Short=OST-alpha; AltName: Full=Solute carrier family 51 subunit alpha [Danio rerio]

Related Sequences to LMP011858 proteins

Reference Database Accession Length Protein Name
GI:52218944 DBBJ BAN16579.1 324 organic solute transporter alpha-1 [Oncorhynchus mykiss]
GI:52218944 EMBL CDQ79530.1 374 unnamed protein product [Oncorhynchus mykiss]
GI:52218944 RefSeq XP_003967925.1 324 PREDICTED: organic solute transporter subunit alpha-like [Takifugu rubripes]
GI:52218944 RefSeq XP_007252358.1 325 PREDICTED: organic solute transporter subunit alpha-like [Astyanax mexicanus]
GI:52218944 RefSeq XP_008296776.1 325 PREDICTED: organic solute transporter subunit alpha-like [Stegastes partitus]
GI:52218944 RefSeq XP_008305803.1 324 PREDICTED: organic solute transporter subunit alpha-like [Cynoglossus semilaevis]