Gene/Proteome Database (LMPD)

LMPD ID
LMP012360
Gene ID
54886
Species
Homo sapiens (Human)
Gene Name
lipid phosphate phosphatase-related protein type 1
Gene Symbol
LPPR1
Synonyms
PRG-3;
Chromosome
9
Map Location
9q31.1
Summary
This gene encodes a member of the plasticity-related gene (PRG) family. Members of the PRG family mediate lipid phosphate phosphatase activity in neurons and are known to be involved in neuronal plasticity. The protein encoded by this gene does not perform its function through enzymatic phospholipid degradation. This gene is strongly expressed in brain. It shows dynamic expression regulation during brain development and neuronal excitation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Orthologs
View orthologs and multiple alignments for LPPR1

Proteins

lipid phosphate phosphatase-related protein type 1
Refseq ID NP_060223
Protein GI 46877064
UniProt ID Q8TBJ4
mRNA ID NM_017753
Length 325
MAVGNNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTDTFQVHIQGFFCQDGDLMKPYPGTEEESFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIAQEKTILTGECCYLNPLLRRIIRFTGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNYTSADCQAHHQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFKGTQGSPSKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT
lipid phosphate phosphatase-related protein type 1
Refseq ID NP_997182
Protein GI 46877066
UniProt ID Q8TBJ4
mRNA ID NM_207299
Length 325
Protein sequence is identical to GI:46877064 (mRNA isoform)

Gene Information

Entrez Gene ID
54886
Gene Name
lipid phosphate phosphatase-related protein type 1
Gene Symbol
LPPR1
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0003824 IEA:InterPro F catalytic activity
GO:0007399 IEA:InterPro P nervous system development

Domain Information

InterPro Annotations

Accession Description
IPR028678 Lipid phosphate phosphatase-related protein type 1
IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase

UniProt Annotations

Entry Information

Gene Name
lipid phosphate phosphatase-related protein type 1
UniProt ID
Q8TBJ4
Species
Human

Comments

Comment Type Description
Similarity Belongs to the PA-phosphatase related phosphoesterase family
Subcellular Location Membrane ; Multi-pass membrane protein

Identical and Related Proteins

Unique RefSeq proteins for LMP012360 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
46877064 RefSeq NP_060223 325 lipid phosphate phosphatase-related protein type 1

Identical Sequences to LMP012360 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP012360 proteins

Reference Database Accession Length Protein Name