Gene/Proteome Database (LMPD)

LMPD ID
LMP012864
Gene ID
114561
Species
Rattus norvegicus (Rat)
Gene Name
phosphatidylinositol transfer protein, beta
Gene Symbol
Pitpnb
Alternate Names
phosphatidylinositol transfer protein beta isoform; PI-TP-beta; ptdInsTP beta; ptdIns transfer protein beta; phosphotidylinositol transfer protein, beta;
Chromosome
12
Map Location
12q16
Summary
complements a yeast sec14 mutation; may act as a phosphotidylinositol transfer protein [RGD, Feb 2006]
Orthologs
View orthologs and multiple alignments for Pitpnb

Proteins

phosphatidylinositol transfer protein beta isoform
Refseq ID NP_446194
Protein GI 16758568
UniProt ID P53812
mRNA ID NM_053742
Length 271
MVLIKEFRVVLPCSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYENDGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGLDPNTWKTVEIVHIDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKELANTPDCPKMCAYKLVTIKFKWWGLQSKVENFIQKQEKRIFTNLHRQLFCWIDKWIDLTMEDIRRMEDETQKELETMRKKGSVRGTSAADA

Gene Information

Entrez Gene ID
114561
Gene Name
phosphatidylinositol transfer protein, beta
Gene Symbol
Pitpnb
Species
Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IEA:UniProtKB-KW C Golgi apparatus
GO:0008289 IEA:UniProtKB-KW F lipid binding
GO:0008526 IMP:RGD F phosphatidylinositol transporter activity
GO:0015914 IMP:GOC P phospholipid transport

Domain Information

InterPro Annotations

Accession Description
IPR001666 Phosphatidylinositol transfer protein
IPR023393 START-like domain

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol transfer protein, beta
Protein Entry
PIPNB_RAT
UniProt ID
P53812
Species
Rat

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P53812-1; Sequence=Displayed; Name=2; IsoId=P53812-2; Sequence=VSP_012763;
Function Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
Ptm Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting
Similarity Belongs to the PtdIns transfer protein family. PI transfer class I subfamily
Subcellular Location Cytoplasm . Golgi apparatus .
Tissue Specificity Expressed abundantly in brain, kidney, liver, and lung, but in a lesser amount in testis.

Identical and Related Proteins

Unique RefSeq proteins for LMP012864 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
16758568 RefSeq NP_446194 271 phosphatidylinositol transfer protein beta isoform

Identical Sequences to LMP012864 proteins

Reference Database Accession Length Protein Name
GI:16758568 DBBJ BAA04669.1 271 phosphatidylinositol transfer protein [Rattus norvegicus]
GI:16758568 SwissProt P53812.2 271 RecName: Full=Phosphatidylinositol transfer protein beta isoform; Short=PI-TP-beta; Short=PtdIns transfer protein beta; Short=PtdInsTP beta [Rattus norvegicus]

Related Sequences to LMP012864 proteins

Reference Database Accession Length Protein Name
GI:16758568 DBBJ BAA04669.1 271 phosphatidylinositol transfer protein [Rattus norvegicus]
GI:16758568 PDB 2A1L 270 Chain A, Rat Pitp-Beta Complexed To Phosphatidylcholine
GI:16758568 SwissProt P53812.2 271 RecName: Full=Phosphatidylinositol transfer protein beta isoform; Short=PI-TP-beta; Short=PtdIns transfer protein beta; Short=PtdInsTP beta [Rattus norvegicus]