Structure Database (LMSD)

Common Name
13S-HpOTrE(gamma)
Systematic Name
13S-hydroperoxy-6Z,9Z,11E-octadecatrienoic acid
Synonyms
LM ID
LMFA02000112
Formula
Exact Mass
Calculate m/z
310.21441
Sum Composition
Status
Curated

Classification

Biological Context

13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.1 Further action of soybean LO-1 converts 13(S)-HpOTrE(γ) to all four isomers of 6,13-DiHOTrE.2 At concentrations greater than 100 µM, 13(S)-HpOTrE(γ) inhibits the activity of soybean LO-1.3

This information has been provided by Cayman Chemical

References

2. Funk, M.O., Isaac, R., and Porter, N.A. Preparation and purification of lipid hydroperoxides from arachidonic and γ-linolenic acids. Lipids 11, 113-116 (1976).
3. Kim, M.R., and Sok, D.E. Irreversible inhibition of soybean lipoxygenase-1 by hydroperoxy acids as substrates. Arch. Biochem. Biophys. 288, 270-275 (1991).

String Representations

InChiKey (Click to copy)
LYFGXCQTRBQQMX-YSHIPJNPSA-N
InChi (Click to copy)
InChI=1S/C18H30O4/c1-2-3-11-14-17(22-21)15-12-9-7-5-4-6-8-10-13-16-18(19)20/h4,6-7,9,12,15,17,21H,2-3,5,8,10-11,13-14,16H2,1H3,(H,19,20)/b6-4-,9-7-,15-12+
SMILES (Click to copy)
C(=C/C/C=C\C=C\C(OO)CCCCC)/CCCCC(=O)O

Other Databases

CHEBI ID
PubChem CID
Cayman ID

Calculated Physicochemical Properties

Heavy Atoms 22
Rings 0
Aromatic Rings 0
Rotatable Bonds 14
Van der Waals Molecular Volume 344.56
Topological Polar Surface Area 66.76
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
logP 5.59
Molar Refractivity 90.16

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Updated at
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