LMPD Database

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LMP006757

UniProt Annotations

Entry Information
Gene Namephosphatidylethanolamine-binding protein 4
Protein EntryPEBP4_HUMAN
UniProt IDQ96S96
SpeciesHuman
Comments
Comment typeDescription
FunctionSeems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization.
InteractionP31749:AKT1; NbExp=2; IntAct=EBI-8563667, EBI-296087; P04049:RAF1; NbExp=4; IntAct=EBI-8563667, EBI-365996;
Sequence CautionSequence=AAH20779.1; Type=Frameshift; Positions=219; Evidence= ; Sequence=AAQ89467.1; Type=Frameshift; Positions=219; Evidence= ;
SimilarityBelongs to the phosphatidylethanolamine-binding protein family.
Subcellular LocationLysosome .
Tissue SpecificityUbiquitously expressed. Highly expressed in tumor cells.