LMPD Database

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LMP007084

UniProt Annotations

Entry Information
Gene NameAkr2p
Protein EntryAKR2_YEAST
UniProt IDQ12013
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityPalmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
CautionIt is uncertain whether Met-1 or Met-4 is the initiator
CautionIt is uncertain whether Met-1 or Met-4 is the initiator. {ECO:0000305}.
DomainThe DHHC domain is required for palmitoyltransferase activity
DomainThe DHHC domain is required for palmitoyltransferase activity. {ECO:0000250}.
FunctionMay be involved in constitutive endocytosis of a-factor receptor STE3
FunctionMay be involved in constitutive endocytosis of a-factor receptor STE3. {ECO:0000269|PubMed:9243510}.
MiscellaneousPresent with 815 molecules/cell in log phase SD medium
MiscellaneousPresent with 815 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily
SimilarityBelongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. {ECO:0000305}.
SimilarityContains 1 DHHC-type zinc finger
SimilarityContains 1 DHHC-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00067}.
SimilarityContains 6 ANK repeats. {ECO:0000255|PROSITE- ProRule:PRU00023}.
Subcellular LocationMembrane; Multi-pass membrane protein.