LMPD Database

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LMP007182

UniProt Annotations

Entry Information
Gene NameN-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13
Protein EntryALG13_YEAST
UniProt IDP53178
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityUDP-N-acetyl-D-glucosamine + N-acetyl-D- glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl- diphosphodolichol.
FunctionInvolved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. {ECO:0000269|PubMed:15615718, ECO:0000269|PubMed:16100110}.
InteractionP38242:ALG14; NbExp=3; IntAct=EBI-23770, EBI-21477;
MiscellaneousPresent with 1950 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the glycosyltransferase 28 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16100110}.
SubunitHeterodimer with ALG14 to form a functional enzyme.