LMPD Database

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LMP007351

UniProt Annotations

Entry Information
Gene NameAre2p
Protein EntryARE2_YEAST
UniProt IDP53629
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + cholesterol = CoA + cholesterol ester.
FunctionEnsures probably most of the acyltransferase activity. Suppression of ARE2 reduces sterol ester levels to 25% of the normal value.
MiscellaneousPresent with 279 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein.