LMPD Database

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LMP009633

UniProt Annotations

Entry Information
Gene Name1,4-dihydroxy-2-naphthoate polyprenyltransferase
Protein EntryMENA_ARATH
UniProt IDQ0WUA3
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q0WUA3-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=2; IsoId=Q0WUA3-2; Sequence=VSP_040861;
Catalytic ActivityAn all-trans-polyprenyl diphosphate + 1,4- dihydroxy-2-naphthoate = a demethylmenaquinol + diphosphate + CO(2). {ECO:0000269|PubMed:15686525}.
Disruption PhenotypeSlower growth and dwarfism. Albino phenotype in aging leaves. Decreased number of chloroplasts, but normal lamellar structure retained. Absence of phylloquinone and 97% decrease in the content of plastoquinone.
FunctionInvolved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 1,4-dihydroxy-2- naphthoate (DHNA). {ECO:0000269|PubMed:15686525}.
SimilarityBelongs to the MenA family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast membrane {ECO:0000269|PubMed:15686525}; Multi-pass membrane protein {ECO:0000269|PubMed:15686525}.