LMPD Database

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LMP009657

UniProt Annotations

Entry Information
Gene Name1-aminocyclopropane-1-carboxylate oxidase 2
Protein EntryACCO2_ARATH
UniProt IDQ41931
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic Activity1-aminocyclopropane-1-carboxylate + ascorbate + O(2) = ethylene + cyanide + dehydroascorbate + CO(2) + 2 H(2)O.
CofactorName=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000255|PROSITE-ProRule:PRU00805, ECO:0000269|PubMed:20018591}; Name=Cu(2+); Xref=ChEBI:CHEBI:29036; Evidence={ECO:0000255|PROSITE-ProRule:PRU00805, ECO:0000269|PubMed:20018591}; Note=Binds 1 Fe(2+) ion per subunit. Can also bind Cu(2+) ions. {ECO:0000255|PROSITE-ProRule:PRU00805, ECO:0000269|PubMed:20018591};
Disruption PhenotypeImpaired in the 1-aminocyclopropane-1- carboxylic acid (ACC)-mediated reversion of the ABA-induced inhibition of seed germination. {ECO:0000269|PubMed:20023197}.
FunctionEnzyme involved in the ethylene biosynthesis. Required to mediate the 1-aminocyclopropane-1-carboxylic acid (ACC)- mediated reversion of the ABA-induced inhibition of seed germination via endosperm rupture. May promote stem elongation by maximizing the extensibility cells, possibly by activating ethylene biosynthesis, in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0). {ECO:0000269|PubMed:17993622, ECO:0000269|PubMed:20023197}.
InductionUpon iron deprivation. Induced by ethylene, particularly in root tips and hooks of ethiolated seedlings. Promoted by ozone O(3). Accumulates in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0). Induced in roots by nitric oxide (NO). {ECO:0000269|PubMed:10409511, ECO:0000269|PubMed:15272873, ECO:0000269|PubMed:15728341, ECO:0000269|PubMed:16920797, ECO:0000269|PubMed:17993622, ECO:0000269|PubMed:20627899, ECO:0000269|PubMed:21316254}.
PathwayAlkene biosynthesis; ethylene biosynthesis via S- adenosyl-L-methionine; ethylene from S-adenosyl-L-methionine: step 2/2.
SimilarityBelongs to the iron/ascorbate-dependent oxidoreductase family. {ECO:0000305}.
SimilarityContains 1 Fe2OG dioxygenase domain. {ECO:0000255|PROSITE-ProRule:PRU00805}.
Tissue SpecificityExpressed in vegetative tissues. Constitutively expressed in leaves and blades. In ethylene exposed etiolated seedlings, localized in cells at the outer side of the exaggerated hook in an ethylene-dependent manner and following an ethylene sensitive pattern. Also detected in the root tip when treated by ethylene. {ECO:0000269|PubMed:10409511, ECO:0000269|PubMed:12972669, ECO:0000269|PubMed:17993622}.