LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins

LMP009804

UniProt Annotations

Entry Information

Gene Name	ALA-interacting subunit 1
Protein Entry	ALIS1_ARATH
UniProt ID	Q9LTW0
Species	Arabidopsis

Comments

Comment type	Description
Function	Required for the lipid transport activity of the ALA/ALIS P4-ATPase complex. {ECO:0000269\|PubMed:18344284, ECO:0000269\|PubMed:20053675}.
Similarity	Belongs to the CDC50/LEM3 family. {ECO:0000305}.
Subcellular Location	Golgi apparatus membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=In a heterologous system, the final intracellular localization after exit from the endoplasmic reticulum is the prevacuolar compartment in the presence of ALA2 and the Golgi in the presence of ALA3.
Subunit	Associates with ALA3 to form a stable complex. Interacts with ALA2 in a heterologous system. {ECO:0000269\|PubMed:18344284, ECO:0000269\|PubMed:20053675}.
Tissue Specificity	Expressed in roots, leaves, stems, flowers and siliques. Found in petals and sepals, but not in reproductive tissues. In siliques, detected in the upper part of the seed pod and in the area between the seed pod and the stem, but not in developing seeds. Strong expression in vascular shoot tissues and in stomatal guard cells of young rosettes leaves. In roots, expressed in cells surrounding the xylem and in central and peripheral columella cells. {ECO:0000269\|PubMed:18344284}.