LMPD Database

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LMP009806

UniProt Annotations

Entry Information
Gene NameALA-interacting subunit 5
Protein EntryALIS5_ARATH
UniProt IDQ8L8W0
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8L8W0-1; Sequence=Displayed; Name=2; IsoId=Q8L8W0-2; Sequence=VSP_036590, VSP_036591; Note=No experimental confirmation available.;
FunctionRequired for the lipid transport activity of the ALA/ALIS P4-ATPase complex. {ECO:0000250}.
Sequence CautionSequence=AAD30230.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BX816946; Type=Frameshift; Positions=183; Evidence={ECO:0000305};
SimilarityBelongs to the CDC50/LEM3 family. {ECO:0000305}.
Subcellular LocationGolgi apparatus membrane {ECO:0000269|PubMed:20053675}; Multi-pass membrane protein {ECO:0000269|PubMed:20053675}. Prevacuolar compartment membrane {ECO:0000269|PubMed:20053675}; Multi-pass membrane protein {ECO:0000269|PubMed:20053675}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:20053675}; Multi-pass membrane protein {ECO:0000269|PubMed:20053675}. Note=In a heterologous system, the final intracellular localization after exit from the endoplasmic reticulum is the prevacuolar compartment in the presence of ALA2 and the Golgi in the presence of ALA3.
SubunitInteracts with ALA2 and ALA3 in a heterologous system. {ECO:0000269|PubMed:18344284, ECO:0000269|PubMed:20053675}.
Tissue SpecificityExpressed in roots, leaves, stems, flowers and siliques. {ECO:0000269|PubMed:18344284}.