LMPD Database

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LMP009851

Record overview

LMPD IDLMP009851
Gene ID840476
SpeciesArabidopsis thaliana (Arabidopsis)
Gene Nameannexin 1
Gene SymbolANNAT1
SynonymsANNEXIN; annexin 1; ANNEXIN A1; ATOXY5; F14D7.2; F14D7_2; OXY5
Alternate namesannexin 1
Chromosome1
SummaryEncodes a member of the annexin gene family, a diverse, multigene family of calcium-dependent, membrane-binding proteins. The protein was determined to have peroxidase activity. This activity is thought to be dependent on the presence of post-translational modifications (most likely phosphorylation). The protein was shown to be present as a mixture of monomer and homodimer. The homodimerization seems to be dependent on the presence of Ca2+ or H2O2. The dimerization was prevented by the addition of DTT, β-mercaptoethanol and TCEP. Annat1 mRNA is expressed in flowers, roots,leaves and stems and is most abundant in stems. mRNA levels are increased in response to oxidative stress. Developmental expression patterns suggest a role in Golgi-mediated polysaccharide secretion.
OrthologsView orthologs and multiple alignments for ANNAT1

Proteins

annexin 1
Refseq ID:NP_174810
Protein GI:15220216
UniProt ID:Q9SYT0
mRNA ID:NM_103274
Length:317
RefSeq Status:REVIEWED
MATLKVSDSVPAPSDDAEQLRTAFEGWGTNEDLIISILAHRSAEQRKVIRQAYHETYGEDLLKTLDKELSNDFERAILLWTLEPGERDALLANEATKRWT
SSNQVLMEVACTRTSTQLLHARQAYHARYKKSLEEDVAHHTTGDFRKLLVSLVTSYRYEGDEVNMTLAKQEAKLVHEKIKDKHYNDEDVIRILSTRSKAQ
INATFNRYQDDHGEEILKSLEEGDDDDKFLALLRSTIQCLTRPELYFVDVLRSAINKTGTDEGALTRIVTTRAEIDLKVIGEEYQRRNSIPLEKAITKDT
RGDYEKMLVALLGEDDA