LMPD Database

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LMP011077

UniProt Annotations

Entry Information
Gene Nameauxin signaling F-box 2
Protein EntryAFB2_ARATH
UniProt IDQ9LW29
SpeciesArabidopsis
Comments
Comment typeDescription
DomainThe F-box is necessary for the interaction with SKP1. {ECO:0000250}.
FunctionComponent of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Confers sensitivity to the virulent bacterial pathogen P.syringae (By similarity). Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. Involved in embryogenesis regulation by auxin. {ECO:0000250, ECO:0000269|PubMed:15917797, ECO:0000269|PubMed:15992545, ECO:0000269|PubMed:16627744}.
InductionRepressed by miR393a (microRNA) in response to flg-22 (flagellin-derived peptide 22). {ECO:0000269|PubMed:16627744}.
PathwayProtein modification; protein ubiquitination.
SimilarityContains 1 F-box domain. {ECO:0000305}.
Subcellular LocationNucleus {ECO:0000269|PubMed:15992545}.
SubunitPart of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity). Interacts with Aux/IAA proteins (IAA7) in an auxin-dependent manner. {ECO:0000250, ECO:0000269|PubMed:15992545}.
Tissue SpecificityUbiquitous, with higer levels in seedlings. {ECO:0000269|PubMed:15992545}.
Web ResourceName=PlantsUBQ; Note=A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants; URL="http://plantsubq.genomics.purdue.edu/";