LMPD Database

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LMP011271

UniProt Annotations

Entry Information
Gene NameAGC (cAMP-dependent, cGMP-dependent and protein kinase C) kinase family protein
Protein EntryOXI1_ARATH
UniProt IDQ9LSF1
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityATP + a protein = ADP + a phosphoprotein.
Developmental StageHighly expressed in fast-growing organs and dividing cells.
Disruption PhenotypePlants have enhanced susceptibility to virulent P.parasitica pathogen and reduced root hair length. {ECO:0000269|PubMed:14749726, ECO:0000269|PubMed:14985766}.
DomainThe activation loop within the kinase domain is the target of phosphorylation. {ECO:0000250}.
Enzyme RegulationActivated in response to hydrogen peroxide and cellulase elicitor. Activated by PDK1 in a phosphatidic acid dependent manner. {ECO:0000269|PubMed:14749726, ECO:0000269|PubMed:14985766}.
FunctionInvolved in oxidative burst-mediated signaling. Required for basal resistance to P.parasitica infection and root hair growth. Partly required for the activation of MPK3 and MPK6 by hydrogen peroxide and cellulase elicitor. {ECO:0000269|PubMed:14985766}.
InductionBy wounding, hydrogen peroxide and cellulase elicitor. {ECO:0000269|PubMed:14985766}.
InteractionO80719:At2g47060; NbExp=4; IntAct=EBI-8574783, EBI-4436376;
SimilarityBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. {ECO:0000305}.
SimilarityContains 1 AGC-kinase C-terminal domain. {ECO:0000305}.
SimilarityContains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}.
SubunitInteracts with PDK1 and PDK2. {ECO:0000269|PubMed:14749726}.
Tissue SpecificityExpressed in roots and root hair cells. {ECO:0000269|PubMed:14749726, ECO:0000269|PubMed:14985766}.