LMPD Database

LMP011632

UniProt Annotations

Entry Information
Gene Name7-dehydrocholesterol reductase
Protein EntryDHCR7_DANRE
UniProt IDQ7SXF1
SpeciesZebrafish
Comments
Comment typeDescription
Catalytic ActivityCholesterol + NADP(+) = cholesta-5,7-dien-3- beta-ol + NADPH.
FunctionProduction of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). {ECO:0000250}.
PathwaySteroid biosynthesis; cholesterol biosynthesis.
SimilarityBelongs to the ERG4/ERG24 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.