LMPD Database

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LMP012455

UniProt Annotations

Entry Information
Gene Nameacetyl-CoA acetyltransferase 1
Protein EntryTHIL_RAT
UniProt IDP17764
SpeciesRat
Comments
Comment typeDescription
Catalytic Activity2 acetyl-CoA = CoA + acetoacetyl-CoA
Enzyme RegulationActivated by potassium ions, but not sodium ions
FunctionPlays a major role in ketone body metabolism.
PtmSuccinylation at Lys-265, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5 (By similarity)
SimilarityBelongs to the thiolase family
Subcellular LocationMitochondrion.
SubunitHomotetramer.