LMPD Database

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LMP012666

UniProt Annotations

Entry Information
Gene Namedelta(4)-desaturase, sphingolipid 1
Protein EntryDEGS1_RAT
UniProt IDQ5XIF5
SpeciesRat
Comments
Comment typeDescription
FunctionHas sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (By similarity)
PtmMyristoylation can target the enzyme to the mitochondria leading to an increase in ceramide levels
SimilarityBelongs to the fatty acid desaturase family. DEGS subfamily
Subcellular LocationMitochondrion. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein .