Lipidomics studies on macrophages - bone marrow-derived macrophages treated with 25-hydroxy-cholesterol +/- lipid-depleted media containing compactin

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Details: CE(20:4) Legend: : View detailed data for replicates: View time course graphs Ctrl: Untreated BMDM cells (control) 25-OHC: Cells treated with 25-OH-cholesterol at time 0 *: BMDM cells in lipid-depleted media containing compactin 25-OHC*: cells in lipid-depleted media containing compactin and treated with 25-OHC at time 0 10.13.75 3.1 6.48 3.02 2 4.8 4.75 4.99 3.53 3.59 2.62 2.03 2.08 7.26 6.08 5.53 5.32 4.87 4.33 3.94 3.16 3.46 3.25 3.24 3.41 2.89 2.08 1.89 1.57 7 6.4 6.04 5.72 6.41 6.75 6.37 8.04 5.35 5.43 4.85 5.44 4.76 2.93 3.28 5.02 - 4.11 4.3 4.61 4.19 3.73 5.11 4.03 0.872 0.934 0.432 0.53 0.083 0.545 0.47 0.438 0.766 0.814 0.948 0.831 1.35 0.499 0.697 0.412 0.086 0.556 0.371 2.6 0.733 0.394 0.333 0.748 0.075 0.559 0.326 2.86 0.78 0.454 0.345 0.674 1.06 1.25 0.455 0.891 0.067 0.424 0.397 0.368 0.641 0.987 0.758 1.01 1.58 0.608 0.706 0.33 0.16 - - 2.03 1.47 2.15 2.13 2.14 2.68 1.43 2.68 1.95 1.95 2.79 7.78 7.59 3.85 7.84 2.02 3.36 5.08 3.87 3.12 4.24 3.18 2.58 2.27 16 78.5 31.8 19 27.6 39.4 27.4 21.4 20.4 51.5 18.3 46.6 75.7 42.1 46.3 33.4 20.1 64.8 76.3 54 114 37.9 44.6 32.9 54.2 31.9 23.7 79.1 55.6 74.8 23 56.5 60.2 47.8 184 341 500 173 189 136 47.2 961 579 61.9 287 287 1148 98.9 512 270 504 388 61.1 159 99.6 111 105 79.2 35.3 456 342 141 34.8 104 19.3 156 98.1 117 22.3 297 Details Graph Individual Expts Ave Biol. Reps LM_ID Name 25-OHC* * 25-OHC Ctrl 0 hrs 25-OHC* * 25-OHC Ctrl 30 min 25-OHC* * 25-OHC Ctrl 1 hr 25-OHC* * 25-OHC Ctrl 2 hrs 25-OHC* * 25-OHC Ctrl 4 hrs 25-OHC* * 25-OHC Ctrl 8 hrs 25-OHC* * 25-OHC Ctrl 12 hrs 25-OHC* * 25-OHC Ctrl 24 hrs Units . . . . Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070914) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070914) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080212) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080219) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCJ080226) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080211) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080311) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD080408) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090512) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090716) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090805) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090805) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMST01020014 CE(20:4) - - - 0.37 0.1 0.12 0.59 1.03 - - 0.43 0.49 0.13 - 0.29 0.41 0.18 - 0.46 0.24 0.14 - 0.46 0.38 0.11 - 0.53 0.39 0.1 - 0.29 0.38 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMST01020014 CE(20:4) - 0.17 - 1.01 0.12 0.21 0.89 1.34 - 0.15 1.11 1.12 0.25 0.15 0.57 0.74 0.3 - 0.38 1.62 0.14 - 0.84 0.83 0.4 - 0.42 3.38 0.23 - 1.28 1.19 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LMST01020014 CE(20:4) - 0.23 - 1.9 0.36 0.3 2.73 2.09 0.24 0.34 2.25 1.85 0.32 0.24 1.37 1.05 0.42 0.17 2.67 3.59 0.41 0.21 1.61 3.07 0.49 0.27 2.27 1.49 1.26 0.26 6.02 1.83 pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100322) LMST01020014 CE(20:4) - - - 3.79 1.14 1.22 6.6 6.86 - - 4.61 5.44 1 - 4.22 5.04 1.31 - 3.59 2.17 1.56 - 6.32 5.8 1.05 - 7.32 5.91 1.18 - 2.93 4.24 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100427) LMST01020014 CE(20:4) - 1.29 - 9.52 1.02 1.86 7.89 14.6 - 1.49 11.1 13 1.9 1.7 6.93 7.97 2.36 - 3.57 11.5 1.43 - 9.98 8.59 3.33 - 4.46 46.9 2.27 - 13.8 11.9 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD100624) LMST01020014 CE(20:4) - 1.84 - 14.2 2.65 1.71 16.2 14.9 1.73 2.14 14.6 13.5 2.24 1.56 7.81 8.2 2.91 1.13 12 16.9 2.75 1.42 12.2 17.2 2.51 1.23 12.2 10.5 6.72 1.28 27.9 9.44 pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090512) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD090716) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE060920) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070616) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070623) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070702) LMST01020014 CE(20:4) pmol/ug DNA Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070802) LMST01020014 CE(20:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070712) LMST01020014 CE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070712) LMST01020014 CE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070712) LMST01020014 CE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (MSE070917) LMST01020014 CE(20:4) pmol/1E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) CE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCD110605) LMST01020014 CE(20:4) pmol/sample Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120120) CE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120131) CE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120212) CE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (BCG120308) LMST01020014 CE(20:4) pmol/10E6 cells Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0010) LMST01020014 CE(20:4) nmol/ml Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp   Legend: :Ctrl  :25-OHC  :Comp  :25-OHC + Comp (NASH0007) LMST01020014 CE(20:4) pmol/mg